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Søren Bak's Publications

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Suzanne Paquette's Publications

A PubMed search of Dr. Møller's work

Søren Bak's profile at KU.

• 2012
  • UDP-glycosyltransferases from the UGT73C Subfamily in Barbarea vulgaris catalyse Sapogenin 3-O-glucosylation in Saponin-mediated Insect resistance.
    Augustin JM, Drok S, Shinoda T, Sanmiya K, Nielsen JK, Khakimov B, Olsen CE, Hansen EH, Kuzina V, Ekstrøm CT, Hauser TP, Bak S
    Plant Physiol. 2012 Oct 3. [Epub ahead of print]
    PMID: 23027665
  • Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile.
    Saito S, Motawia MS, Olsen CE, Møller BL, Bak S
    Phytochemistry. 2012 May;77:260-7. Epub 2012 Mar 3
    PMID: 22385904
• 2011
  • Chapter, "Cytochromes P450" in The Arabidopsis Book.
    Bak S, Beisson F, Bishop G, Hamberger B, Höfer R, Paquette S, Werck-Reichhart D, ed. R Last
    American Society of Plant Biologists. Rockville, MD. October 6, 2011 doi: 10.1199/tab.0144
    http://www.aspb.org/publications/arabidopsis/
  • Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects
    Jensen NB, Zagrobelny M, Hjernø K, Olsen CE, Houghton-Larsen J, Borch J, Møller BL, Bak S
    Nat Commun. 2011;2:273.
    PubMed PMID: 21505429
  • Molecular activities, biosynthesis and evolution of triterpenoid saponins
    Augustin JM, Kuzina V, Andersen SB, Bak S
    Phytochemistry 72:435-457 (2011) Epub 2011 Feb 16.
    PMID: 21333312
  • Barbarea vulgaris linkage map and quantitative trait loci for saponins, glucosinolates, hairiness and resistance to the herbivore Phyllotreta nemorum
    Kuzina V, Nielsen JK, Augustin JM, Torp AM, Bak S, Andersen SB
    Phytochemistry 72(2-3):188-98 (2011) Epub 2010 Dec 2.
    PMID: 21130479
  • Biosynthesis of the Cyanogenic Glucosides Linamarin and Lotaustralin in Cassava: Isolation, Biochemical Characterization, and Expression Pattern of CYP71E7, the Oxime-Metabolizing Cytochrome P450 Enzyme
    Jørgensen K, Morant AV, Morant M, Jensen NB, Olsen CE, Kannangara R, Motawia MS, Møller BL, Bak S
    Plant Physiology 155:282-292 (2011) Epub 2010 Nov 3.
    PMID: 21045121
• 2010
  • Metabolomic, transcriptional, hormonal, and signaling cross-talk in Superroot2
    Morant M, Ekstrøm C, Ulvskov P, Kristensen C, Rudemo M, Olsen CE, Hansen J, Jørgensen K, Jørgensen B, Møller BL, Bak S
    Mol Plant. 2010 Jan;3(1):192-211. Epub 2009 Dec 14.
    PMID: 20008451
• 2009
  • 454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis and turnover of cyanogenic glucosides
    Zagrobelny M, Scheibye-Alsing K, Jensen NB, Møller BL, Gorodkin J, Bak S
    BMC Genomics 10:574 (2009)
    PMID: 1995453
  • Identification of Defense Compounds in Barbarea vulgaris against the Herbivore Phyllotreta nemorum by an Ecometabolomic Approach
    Kuzina V, Ekstrøm CT, Andersen SB, Nielsen JK, Olsen CE, Bak S
    Plant Physiol. 2009 Dec;151(4):1977-90. Epub 2009 Oct 9
    PMID: 19819983
    
  • A web-based resource for the Arabidopsis P450, cytochromes b₅, NADPH-cytochrome P450 reductases, and Family 1 glycosyltransferases (http://www.P450.kvl.dk)
    Paquette SM, Jensen K, Bak S
    Phytochemistry. 2009 Dec;70(17-18):1940-7. Epub 2009 Oct 8
    PMID: 19818975
    
  • Effect of Glucuronosylation on Anthocyanin Color Stability
    Osmani SA, Halkjær Hansen E, Malien-Aubert C, Olsen CE, Bak S, Møller BL
    J Agric Food Chem 2009 Apr 22;57(8):3149-55. Epub 2009 Mar 12
    PMID: 19281238
  • Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling
    Osmani SA, Bak S, Møller BL
    Phytochemistry 2009 Feb;70(3):325-347. Epub 2009 Feb 13
    PMID: 19217634
• 2008
  • Cyanogenic glucosides as determinants of feeding preferences in Zygaena filipendulae.
    Zagrobelny M, Bak S, Møller BL
    Symposium International Sur Les Zygaenidae. Écologie Et Phylogénie Des Zygaenidae De La Zone Paléarctique. (Drouet E ed) pp 113-122, Lyon. (2008)
  • Catalytic Key Amino Acids and UDP Sugar Donor Specificity of a Plant Glucuronosyl Transferase, UGT94B1. Molecular Modeling Substantiated by Site-Specific Mutagenesis and Biochemical Analyses
    Osmani SA, Bak S, Imberty A, Olsen CE, Møller BL
    Plant Physiol 2008 Nov;148(3):1295-308. Epub 2008 Oct 1
    PMID: 18829982
  • The β-glucosidases responsible for bio-activation of hydroxynitrile glucosides in Lotus japonicus
    Morant AV, Bjarnholt N, Kragh ME, Kjargaard CH, Jørgensen K, Paquette SM, Piotrowski M, Imberty A, Olsen CE, Møller BL, Bak S
    Plant Physiol 2008 Jul;147(3):1072-91. Epub 2008 May 8
    PMID: 18472115
  • Cyanogenesis in Plants and Arthropods
    Zagrobelny M, Bak S, Møller BL
    Phytochemistry 2008 May;69(7):1457-68. Epub 2008 Mar 18
  • Diversification of an ancient theme: Hydroxynitrile glucosides
    Bjarnholt N, Rook F, Motawia MS, Cornett C, Jørgensen C, Olsen CE, Jaroszewski JW, Bak S, Møller BL
    Phytochemistry 2008 May;69(7):1507-16. Epub 2008 Mar 14
  • β-Glucosidases as Detonators of Plant Chemical Defense
    Morant AV, Jørgensen K, Paquette SM, Sánchez-Pérez R, Møller BL, Bak S
    Phytochemistry 2008 Jun;69(9):1795-813. Epub 2008 May 9
• 2007
  • Intimate roles for cyanogenic glucosides in the life cycle of Zygaena filipendulae (Lepidoptera, Zygaenidae)
    Zagrobelny M, Bak S, Olsen CE, Møller BL
    Insect Biochem Mol Biol 2007 Nov;37(11):1189-97 Epub 2007 Jul 25
  • Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism.
    Jenrich R, Trompetter I, Bak S, Olsen CE, Møller BL, Piotrowski M
    Proc Natl Acad Sci U S A 2007 Nov 20;104(47):18848-53. Epub 2007 Nov 14
  • Lessons learned from metabolic engineering of cyanogenic glucosides
    Morant AV, Jørgensen K, Jørgensen B, Dam W, Olsen CE, Møller BL, Bak S
    METABOLOMICS 3 (3): 383-398 SEP 2007
  • CYP703 is an ancient cytochrome P450 in land plants catalyzing in chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen.
    Morant M, Jørgensen K, Schaller H, Pinot F, Møller BL, Werck-Reichhart D, Bak S
    Plant Cell 2007 May;19(5):1473-87. Epub 2007 May 11
  • The cyanogenic glucoside composition of Zygaena filipendulae (Lepidoptera: Zygaenidae) as effected by feeding on wild-type and transgenic lotus populations with variable cyanogenic glucoside profiles
    Zagrobelnya M, Bak S, Ekstrøm CT, Olsen CE, Møller BL.
    Insect Biochem Mol Biol. 2007 Jan;37(1):10-8. Epub 2006 Oct 4
• 2006
  • Cyanogenic glycosides: a case study for evolution and application of cytochromes P450
    Bak S, Paquette SM, Morant M, Rasmussen AV, Saito S, Bjarnholt N, Zagrobelny M, Jørgensen K, Hamann T, Osmani S, Simonsen HT, Pérez RS, van Hesswijck TB, Jørgensen B, Møller BL
    Phytochemistry Reviews. 2006 Jun;5(2-3):309-329 Epub 2006 November 15
• 2005
  • Determination of catalytic key amino acids and UDP-sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor: molecular modeling substantiated by site specific mutagenesis and biochemical analyses.
    Thorsøe KS, Bak S, Olsen CE, Imberty A, Breton C, Møller BL
    Plant Physiol 2005 Oct;139(2):664-73. Epub 2005 Sep 16
  • Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology.
    Jorgensen K, Bak S, Busk PK, Sorensen C, Olsen CE, Puonti-Kaerlas J, Møller BL.
    Plant Physiol 2005 Sep;139(1):363-74 Epub 2005 Aug 26
  • Genetic engineering, natural variation and substantial equivalence
    Møller BL and Bak S.
    Trends in Biotechnology Volume 23, Issue 8, August 2005, Pages 383-384
    
  • Metabolon formation and metabolic channeling in the biosynthesis of secondary metabolites.
    Jørgensen K, Rasmussen AV, Morant M, Nielsen AH, Bjarnholt N, Zagrobelny M, Bak S, Møller BL.
    Curr Opin Plant Biol 2005 Jun;8(3):280-91
  • Pixel-level Signal Modelling with Spatial Correlation for Two-Colour Microarrays
    Ekstrøm CT, Bak S, Rudemo M.
    Stat App Gen and Mol Biol 4: article 6 (2005) The Berkeley Electronic Press
  • Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome.
    Kristensen C, Morant M, Olsen CE, Ekstrøm CT, Galbraith DW, Møller BL, Bak S.
    Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1779-84 Epub 2005 Jan 21
  • Functional Genomics of the Cytochrome P450 Gene Superfamily in Arabidopsis thaliana
    Galbraith DW, and Bak S.
    pp. 595-620 (2005) In: Plant Functional Genomics (D. Leister, ed.). The Haworth Press Inc. Binghamton, NY, USA.
    ISBN: 1-56022-998-5 (hardbound), 1-56022-999-3 (softbound)
• 2004
  • Comparative genomics of Oryza sativa and Arabidopsis thaliana: Analysis of 727 Cytochrome P450 genes and pseudogenes from a monocot and a dicot.
    Nelson DR, Schuler MA, Paquette SM, Werck-Reichhart D, Bak S.
    Plant Physiol 2004 Jun;135(2):756-72
  • Spot shape modelling and data transformations for microarrays.
    Ekstrøm CT, Bak S, Kristensen C, Rudemo M.
    Bioinformatics 2004 Sep 22;20(14):2270-8. Epub 2004 Apr 1
  • Biosynthesis of the Nitrile Glucosides Rhodiocyanoside A and D and the Cyanogenic Glucosides Lotaustralin and Linamarin in Lotus japonicus
    Forslund K, Morant M, Jorgensen B, Olsen CE, Asamizu E, Sato S, Tabata S, Bak S.
    Plant Physiol. 2004;135 71-84
  • Cyanogenic glucosides and plant-insect interactions.
    Zagrobelny M, Bak S, Rasmussen AV, Jørgensen B, Naumann CM, Møller BL.
    Phytochemistry. 2004 Feb;65(3):293-306
• 2003
  • CYP83A1 and CYP83B1, Two Nonredundant Cytochrome P450 Enzymes Metabolizing Oximes in the Biosynthesis of Glucosinolates in Arabidopsis
    Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, and Halkier BA.
    Plant Physiol. 2003 Sep;133(1):63-72
  • The in vitro substrate regiospecificity of UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor.
    Hansen KS, Kristensen C, Tattersall DB, Jones PR, Olsen CE, Bak S, and Møller BL.
    Phytochemistry (2003) 64(1):143-51
  • Cytochromes P450s: tools for pharmacology, phytoremediation and plant protection.
    Morant M, Bak S, Møller BL, Werck-Reichhart D.
    Curr Opin in Biotechnol (2003) 14(2):151-62
  • On the Origin of Family 1 Plant Glycosyltransferases.
    Paquette SM, Lindberg Møller B, Bak S.
    Phytochemistry (2003) 62:399-413.
    Requests for a PDF file of the accepted manuscript should be sent to Søren Bak.
  • CYP79B1 from Sinapis alba converts tryptophan to indole-3-acetaldoxime.
    Naur P, Hansen CH, Bak S, Hansen BG, Jensen NB, Nielsen HL, Halkier BA.
    Arch Biochem Biophys. 2003 Jan 1;409(1):235-241.
  • Chapter, "Cytochromes P450" in The Arabidopsis Book.
    Werck-Reichhart D, Bak S, Paquette S., eds. C.R. Somerville and E.M. Meyerowitz.
    American Society of Plant Biologists. Rockville, MD. doi/10.1199/tab.0028
    http://www.aspb.org/publications/arabidopsis/
• 2001
  • Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis.
    Tattersall DB, Bak S, Jones PR, Olsen CE, Nielsen JK, Hansen ML, Høj PB, and Møller BL.
    Science. 2001 Sep 7;293(5536):1826-8.
    
  • Microarray-based analysis of gene expression in very large gene families: the Cytochrome P450 gene superfamily of Arabidopsis thaliana
    Xu W, Bak S, Decker A, Paquette SM, Feyereisen R, and Galbraith DW.
    Gene 2001 Jul 11;272(1-2):61-74
  • The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis.
    Bak s, Feyereisen R
    Plant Physiol. 2001 Sep;127(1):108-18.
  • Plant sterol 14alpha-demethylase affinity for azole fungicides.
    Lamb DC, Cannieux M, Warrilow AG, Bak S, Kahn RA, Manning NJ, Kelly DE, Kelly SL.
    Biochem Biophys Res Commun 2001 284(3):845-9
  • Chacterization of transgenic Arabidopsis thaliana with metabolically engineered high levels of p-hydrobenzylglucosinolate.
    Petersen BL, Andréasson E, Bak S, Agerbirk N, Halkier BA.
    Planta (2001) 212:612-618
  • CYP83B1, a cytochrome P450 at the metabolic branchpoint in auxin and indole glucosinolate biosynthesis in Arabidopsis thaliana.
    Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R.
    The Plant Cell (2001) 13(1):101-111
• 2000
  • Transgenic tobacco and Arabidopsis plants expressing the two multifunctional sorghum cytochromes P450, CYP79A1 and CYP71E1, are cyanogenic and accumulate metabolites derived from intermediates in dhurrin biosynthesis.
    Bak S, Olsen CE, Halkier BA, and Møller BL.
    Plant Physiology (2000) 123 (4):1437-1448
  • Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana.
    Paquette SM, Bak S, Feyereisen R.
    DNA and Cell Biology (2000) 19 (5):307-17
    Requests for a PDF file of the manuscript should be sent to Søren Bak.
• 1999
  • Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor.
    Bak S, Olsen CE, Petersen BL, Møller BL, and Halkier BA.
    Plant Journal (1999) 20:663-672
  • Optimized expression and catalytic properties of a wheat obtusifoliol 14alpha-demethylase (CYP51) expressed in yeast Complementation of erg11Delta yeast mutants by plant CYP51.
    Cabello-Hurtado F, Taton M, Forthoffer N, Kahn R, Bak S, Rahier A, Werck-Reichhart D.
    Eur J Biochem. 1999 Jun 1;262(2):435-446
• 1998
  • Two cases of non-host resistance against potyviruses operating at the single cell level.
    Bak S, Poulsen GB, and Albrechtsen M.
    Journal of Phytopathology (1998) 146:623-629
  • The presence of CYP79 homologues in glucosinolate-producing plants shows evolutionary conservation of the enzymes in the conversion of amino acid to aldoxime in the biosynthesis of cyanogenic glucosides and glucosinolates.
    Bak S, Nielsen HL, Halkier BA.
    Plant Mol Biol. 1998 Nov;38(5):725-34
  • Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin.
    Bak S, Kahn RA, Nielsen HL, Møller BL, Halkier BA.
    Plant Mol Biol. 1998 Feb;36(3):393-405
• 1997
  • Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals.
    Bak S, Kahn RA, Olsen CE, Halkier BA
    Plant J. 1997 Feb;11(2):191-201
  • Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum.
    Kahn RA, Bak S, Svendsen I, Halkier BA, Møller BL.
    Plant Physiol. 1997 Dec;115(4):1661-70
• 1996
  • Isolation and reconstitution of the heme-thiolate protein obtusifoliol 14 alpha-demethylase from Sorghum bicolor (L.) Moench.
    Kahn RA, Bak S, Olsen CE, Svendsen I, Møller BL.
    J Biol Chem. 1996 Dec 20;271(51):32944-50.
  • Possible use of a biotechnological approach to optimise and regulate the content and distribution of cyanogenic glucosides in cassava (Manihot esculenta Crantz) to increase food safety.
    Koch BM, Sibbesen O, Swain E, Kahn RA, Du L, Bak S, Halkier BA, Møller BL.
    Acta Horticultura (1994) 375:45-60

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